| Topic | Lecturer |
| The Character, customs, costumes, etc. of the North American Indians | George Catlin |
| Causes of the American Revolution | Jared Sparks |
| The Sun | Hubbard Winslow |
| The Sources of National Wealth | C. H. Brewster |
| Common School Education | C. T. Torrey |
| The Capacity of the Human Mind for Culture and Improvement | Ephraim Peabody |
| The Honey Bee | H. K. Oliver |
| Popular Education | R. C. Winthrop |
| Geology | Prof. C. B. Adams |
| The Legal Rights of Women | Simon Greenleaf |
| Instinct | Henry Ware, Jr. |
| Life of Mohammed | J. H. Ward |
| Life and Times of Oliver Cromwell | H. W. Kinsman |
| Memoirs of Count Rumford | A. C. Peirson |
| The Practical Man | Convers Francis |
| The Poet of Natural History | J. L. Russell |
| The Progress of Democracy | John Wayland |
| The Discovery of America by the Northmen | A. H. Everett |
| The Satanic School of Literature and Its Reform | Samuel Osgood |
| The Education of Children | Horace Mann |