Derivation signal=noiseless underlying signal n1=random noise present in measurement 1, average value = zero n2=random noise present in measurement 2 (Separate sample, same population) sdn=standard deviation of n1 or n2 (same population, on average equal) measurement 1: m1=signal+n1 measurement 2: m2=signal+n2 (signal is exactly the same in both) difference=m1-m2, so that the signal cancels out exactly, leaving n1-n2, the standard deviation of which is LARGER than that of n1 or n2 separately, because it's composed of TWO independent noises. To figure this out, we must use the rules for error propagation. When two random variables are added or subtracted, the standard deviation of the result is the square root of the sum of the squares of the individual standard deviations. In other words: std(m1-m2) = std(n1-n2) = sqrt(std(sdn)^2 + std(sdn)^2) Square both sides: std(m1-m2).^2 = std(sdn)^2 + std(sdn)^2 Combine terms on right side: std(m1-m2).^2 = 2*(std(sdn)^2) Divide both sides by 2: (std(m1-m2).^2)/2 = std(sdn)^2) Take square root of both sides sqrt((std(m1-m2).^2)/2) = std(sdn) QED Reference: See the first line of https:// terpconnect.umd.edu/~toh/spectrum/ErrorPropagation.pdf)