Answer for Problem 3The total number of tablets ingested must be based on the amount of drug found in the gastric fluid as well as in the blood. The mass of drug found in the gastric fluid was:
mass = (concentration)(volume) = (820 mg/L) (0.450 L) = 369 mg
The mass of drug found in the blood was:mass = (Vd)(mass)(concentration) = (3.5 L/kg)(120 lb)(0.454 kg/lb)(2.5mg/L) = 477 mg
Thus, the total mass of drug ingested was369 + 477 mg = 846 mg
and the number of tablets must have been:Gastric contents: 369 mg /(60 mg/tablet) = 6 tablet
Total contents : 846 mg/(60 mg/tablet) = 14 tablets
The large number of tablets in the gastric fluid and the large total number are both consistent with a suicide.
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