Material Safety Data
Section 1 - Chemical Product and Company
MSDS Name: Toluene
Numbers: S80229, S80229-1, S80229-2, S802292MF, S80229HPLC, S80229SPEC,
BP2625100, BPT290-1LC, BPT290RS-115, BPT290RS-200, BPT290RS-28, BPT290RS-50,
NC9475555, NC9631713, NC9872406, T288-1, T288POP19, T288POP200, T288POP50,
T288RS19, T288SS19, T288SS200, T288SS50, T289-4, T290 1, T290 4, T290-1, T290-4,
T2901, T2901LC, T2904, T290J4, T290N219, T290NB219, T290POP19, T290POP200,
T290POP50, T290POPN19, T290RS115, T290RS19, T290RS200, T290RS28, T290RS50,
T290SK 1, T290SK 4, T290SK-1, T290SK-4, T290SK1, T290SK4, T290SS115, T290SS19,
T290SS200, T290SS28, T290SS50, T291 4, T291-4, T2914, T2914LC, T2914LOT004,
T2914LOT009, T2914LOT010, T291J4, T291RS200, T313 4, T313-4, T3134, T313SK 4,
T313SK-4, T313SK4, T323 20, T323 4, T323-20, T323-4, T32320, T3234, T324 1, T324
20, T324 200, T324 4, T324 500, T324-1, T324-20, T324-200, T324-4, T324-500,
T3241, T32420, T32420 001, T324200, T32420001, T324200LC, T32420LC, T3244,
T324500, T324CU1300, T324FB115, T324FB19, T324FB200, T324FB50, T324J4, T324J500,
T324POP19, T324POP200, T324POP50, T324POPB19, T324POPB200, T324POPB50,
T324RB115, T324RB19, T324RB200, T324RB50, T324RS115, T324RS19, T324RS200,
T324RS28, T324RS50, T324S 4, T324S-4, T324S4, T324SK 4, T324SK-4, T324SK4,
T324SK4LC, T324SS115, T324SS19, T324SS200, T324SS28, T324SS50, T326-P4, T32620,
T326F1GAL, T326P4, T326S20, T330 4, T330-4, T3304, XXT324200LI
Synonyms: Methacide; Methylbenzene; Methylbenzol; Phenylmethane;
1 Reagent Lane
Lawn, NJ 07410
For information, call: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 -
Composition, Information on Ingredients
Symbols: XN F
Risk Phrases: 11 20
Section 3 - Hazards
Appearance: colorless liquid. Flash Point: 40 deg F. Flammable liquid and
vapor. May cause central nervous system depression. May cause liver and
kidney damage. This substance has caused adverse reproductive and fetal effects
in animals. Causes digestive and respiratory tract irritation. May cause skin
irritation. Aspiration hazard if swallowed. Can enter lungs and cause
damage. Danger! Harmful or fatal if swallowed. Causes eye
irritation and possible transient injury. Poison! May be absorbed through intact
skin. Vapor harmful. Call physician immmediately.
Kidneys, central nervous system, liver.
Eye: Causes eye irritation. May result
in corneal injury. Vapors may cause eye irritation.
May cause skin irritation. Prolonged and/or repeated contact may cause
irritation and/or dermatitis. May be absorbed through the skin.
Ingestion: Aspiration hazard. May cause irritation of the
digestive tract. May cause effects similar to those for inhalation exposure.
Aspiration of material into the lungs may cause chemical pneumonitis, which may
Inhalation: Inhalation of high concentrations may
cause central nervous system effects characterized by nausea, headache,
dizziness, unconsciousness and coma. Inhalation of vapor may cause respiratory
tract irritation. May cause liver and kidney damage. Vapors may cause dizziness
or suffocation. Overexposure may cause dizziness, tremors, restlessness, rapid
heart beat, increased blood pressure, hallucinations, acidosis, kidney failure.
Chronic: Prolonged or repeated skin contact may cause
dermatitis. May cause cardiac sensitization and severe heart abnormalities. May
cause liver and kidney damage.
Section 4 - First Aid
Eyes: Flush eyes with plenty of water for at least
15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid
Skin: Flush skin with plenty of water for at
least 15 minutes while removing contaminated clothing and shoes. Get medical aid
if irritation develops or persists.
Ingestion: Do NOT
induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or
water. Never give anything by mouth to an unconscious person. Possible
aspiration hazard. Get medical aid immediately.
Get medical aid immediately. Remove from exposure and move to fresh air
immediately. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen.
Notes to Physician: Causes cardiac
sensitization to endogenous catelcholamines which may lead to cardiac
arrhythmias. Do NOT use adrenergic agents such as epinephrine or
Section 5 - Fire
Information: Containers can build up pressure if exposed to heat and/or
fire. As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Water runoff can cause environmental damage. Dike and collect water used to
fight fire. Vapors may form an explosive mixture with air. Vapors can travel to
a source of ignition and flash back. Flammable Liquid. Can release vapors that
form explosive mixtures at temperatures above the flashpoint. Use water spray to
keep fire-exposed containers cool. Water may be ineffective. Material is lighter
than water and a fire may be spread by the use of water. Vapors may be heavier
than air. They can spread along the ground and collect in low or confined areas.
Containers may explode when heated.
Use water spray to cool fire-exposed containers. Water may be ineffective. Do
NOT use straight streams of water. For small fires, use dry chemical, carbon
dioxide, water spray or regular foam. Cool containers with flooding quantities
of water until well after fire is out. For large fires, use water spray, fog or
Flash Point: 40e deg F ( 4.44 deg C)
Autoignition Temperature: 896 deg F ( 480.00 deg C)
(estimated) Health: 2; Flammability: 3; Instability: 0
Section 6 -
Accidental Release Measures
Information: Use proper personal protective equipment as indicated in
Spills/Leaks: Avoid runoff into storm sewers and
ditches which lead to waterways. Remove all sources of ignition. Absorb spill
using an absorbent, non-combustible material such as earth, sand, or
vermiculite. Do not use combustible materials such as saw dust. A vapor
suppressing foam may be used to reduce vapors. Water spray may reduce vapor but
may not prevent ignition in closed spaces.
Section 7 - Handling
Handling: Wash thoroughly after handling. Use with
adequate ventilation. Ground and bond containers when transferring material.
Avoid contact with eyes, skin, and clothing. Empty containers retain product
residue, (liquid and/or vapor), and can be dangerous. Keep container tightly
closed. Avoid contact with heat, sparks and flame. Avoid ingestion and
inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose
empty containers to heat, sparks or open flames.
Keep away from heat, sparks, and flame. Keep away from sources of ignition.
Store in a tightly closed container. Store in a cool, dry, well-ventilated area
away from incompatible substances.
Section 8 - Exposure
Controls, Personal Protection
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the permissible
||50 ppm TWA; skin - potential for cutaneous absorption
||100 ppm TWA; 375 mg/m3 TWA 500 ppm IDLH
||200 ppm TWA; 300 ppm
OSHA Vacated PELs:
Toluene: 100 ppm TWA; 375 mg/m3 TWA
Eyes: Wear appropriate protective
eyeglasses or chemical safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin
Clothing: Wear appropriate protective clothing to
prevent skin exposure.
Respirators: Follow the OSHA respirator
regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - Physical
and Chemical Properties
Odor: sweetish odor -
pH: Not available.
Vapor Pressure: 36.7 mm
Hg @ 30C
Vapor Density: 3.1 (Air=1)
Viscosity: 0.59 cP @ 20C
232 deg F
Freezing/Melting Point:-139 deg F
Section 10 -
Stability and Reactivity
Stability: Stable under normal temperatures and pressures.
to Avoid: Incompatible materials, ignition sources, excess heat.
Incompatibilities with Other Materials: Ntrogen tetroxide, nitric
acid + sulfuric acid, silver perchlorate, strong oxidizers, sodium dilfuoride, .
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 -
CAS# 108-88-3: XS5250000
Draize test, rabbit, eye: 870 ug Mild;
Draize test, rabbit, eye:
2 mg/24H Severe;
Draize test, rabbit, skin: 435 mg Mild;
rabbit, skin: 500 mg Moderate;
Draize test, rabbit, skin: 20 mg/24H
Inhalation, mouse: LC50 = 400 ppm/24H;
Inhalation, rat: LC50 =
Oral, rat: LD50 = 636 mg/kg;
Skin, rabbit: LD50 = 14100
A4 - Not Classifiable as a Human Carcinogen
IARC: IARC Group 3 - not
Epidemiology: No information available.
Teratogenicity: Specific developmental abnormalities included
craniofacial effects involving the nose and tongue, musculoskeletal effects,
urogenital and metabolic effects in studies on mice and rats by the inhalation
and oral routes of exposure. Some evidence of fetotoxicity with reduced fetal
weight and retarded skeletal development has been reported in mice and rats.
Reproductive Effects: Effects on fertility such as abortion were
reported in rabbits by inhalation. Paternal effects were noted in rats by
inhalation. These effects involved the testes, sperm duct and epididymis.
Neurotoxicity: No information available.
Other Studies: See actual entry in RTECS for
Section 12 -
data available. Bluegill LC50=17 mg/L/24H Shrimp LC50=4.3 ppm/96HFathead minnow
LC50=36.2 mg/L/96HSunfish (fresh water) TLm=1180 mg/L/96H
Environmental: From soil, substance evaporates and is microbially
biodegraded. In water, substance volatilizes and biodegrades.
Physical: Photochemically produced hydroxyl radicals degrade
Section 13 - Disposal
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 108-88-3:
waste number U220.
Section 14 -
||FLASHPOINT 4 C|
Section 15 -
CAS# 108-88-3 is listed on the TSCA
Health & Safety Reporting List
Effective Date: 10/4/82; Sunset Date: 10/4/92
None of the chemicals in this product are under a Chemical Test
None of the chemicals are listed under TSCA
TSCA Significant New Use Rule
None of the chemicals
in this material have a SNUR under TSCA.
Hazardous Substances and corresponding RQs
CAS# 108-88-3: 1000 lb final
RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous
None of the chemicals in this product have a TPQ.
CAS # 108-88-3: acute, flammable.
material contains Toluene (CAS# 108-88-3, 99%),which is subject to the reporting
requirements of Section 313 of SARA Title III and 40 CFR Part 373.
CAS# 108-88-3 is listed as a hazardous air pollutant (HAP). This
material does not contain any Class 1 Ozone depletors. This material does not
contain any Class 2 Ozone depletors.
Clean Water Act:
108-88-3 is listed as a Hazardous Substance under the CWA. CAS# 108-88-3 is
listed as a Priority Pollutant under the Clean Water Act. CAS# 108-88-3 is
listed as a Toxic Pollutant under the Clean Water Act.
of the chemicals in this product are considered highly hazardous by OSHA.
CAS# 108-88-3 can be found on the following state right to
know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
WARNING: This product contains Toluene, a chemical known to the state of
California to cause birth defects or other reproductive harm. California No
Significant Risk Level: None of the chemicals in this product are listed.
Labeling in Accordance with EC Directives
R 11 Highly flammable.
R 20 Harmful by
S 16 Keep away from sources of
ignition - No
S 25 Avoid contact with eyes.
S 29 Do not
empty into drains.
S 33 Take precautionary measures against static
WGK (Water Danger/Protection)
CAS# 108-88-3: 2
Canada - DSL/NDSL
CAS# 108-88-3 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B.
Canadian Ingredient Disclosure List
CAS# 108-88-3 is listed on the
Canadian Ingredient Disclosure List.
OEL-AUSTRALIA:TWA 100 ppm (375 mg/m3);STEL 150 ppm (5
OEL-BELGIUM:TWA 100 ppm (377 mg/m3);STEL 150 ppm (565 mg/m3
OEL-CZECHOSLOVAKIA:TWA 200 mg/m3;STEL 1000 mg/m3 OEL-DENMARK:TWA 5
0 ppm (190
mg/m3);Skin OEL-FINLAND:TWA 100 ppm (375 mg/m3);STEL 150 p
OEL-FRANCE:TWA 100 ppm (375 mg/m3);STEL 150 ppm (560 mg/m3)
100 ppm (380 mg/m3) OEL-HUNGARY:TWA 100 mg/m3;STEL 30
OEL-JAPAN:TWA 100 ppm (380 mg/m3) OEL-THE NETHERLANDS:T
WA 100 ppm (375
mg/m3);Skin OEL-THE PHILIPPINES:TWA 100 ppm (375 mg/m
3) OEL-POLAND:TWA 100
mg/m3 OEL-RUSSIA:TWA 100 ppm;STEL 50 mg/m3 OE
L-SWEDEN:TWA 50 ppm (200
mg/m3);STEL 100 ppm (400 mg/m3);Skin OEL-SWI
TZERLAND:TWA 100 ppm (380
mg/m3);STEL 500 ppm OEL-THAILAND:TWA 200 pp
m;STEL 300 ppm OEL-TURKEY:TWA 200
ppm (750 mg/m3) OEL-UNITED KINGDOM
:TWA 100 ppm (375 mg/m3);STEL 150 ppm;Skin
OEL IN BULGARIA, COLOMBIA,
JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND,
check ACGI TLV
Section 16 -
MSDS Creation Date:
Revision #4 Date: 11/04/2002
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
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for lost profits or any special, indirect, incidental, consequential or
exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.