Material Safety Data
Section 1 - Chemical Product and Company
MSDS Name: Ethyl acetate
Catalog Numbers: AC149470010, AC149470025, AC149470250,
AC167810010, AC167810025, AC167815000, AC232110010, AC232110025, AC268350010,
AC268350025, AC268350040, AC326610010, AC326610025, AC326901000, AC326902500,
AC327880010, AC364350010, AC364350025, AC364351000, AC423175000, AC423680010,
AC423680040, AC423685000, AC610060040, AC610170040, AC610341000, S75118, S80003,
S80004, BP1125-1, BP1125-4, E124-20, E124-4, E124POP200, E124RS200, E124SS200,
E145-1, E145-20, E145-200, E145-4, E145-500, E14520LC, E1454LC, E145FB115,
E145FB19, E145FB200, E145FB50, E145POP19, E145POP200, E145POP50, E145POPB19,
E145POPB200, E145POPB50, E145RB115, E145RB19, E145RB200, E145RB50, E145RS115,
E145RS200, E145RS28, E145RS50, E145S-4, E145SK-4, E145SS115, E145SS19,
E145SS200, E145SS28, E145SS50, E189-4, E191-4, E195-1, E195-4, E195N119,
E195N219, E195NB219, E195POP19, E195POP200, E195POP50, E195POPN19, E195RS115,
E195RS200, E195RS50, E195SK-1, E195SK-4, E195SK4001, E195SK4002, E195SK4003,
E195SK4004, E195SK4005, E195SK4006, E195SK4007, E195SK4008, E195SK4009,
E195SK4010, E195SS115, E195SS19, E195SS200, E195SS50, E196-4, E1964LC,
E1964LOT012, E196POP19, E196POP200, E196POP50, E196RS115, E196RS19, E196RS200,
E196RS28, E196RS50, E196SS115, E196SS19, E196SS200, E196SS28, E196SS50, E1984LC,
E95NB219, E95SS19, NC9728400, NC9761812, 23-005-51, 23-005-68
Synonyms: Acetic acid, ethyl ester; Acetic ether; Acetidin;
Acetoxyethane; Ethyl acetic ester; Ethyl ethanoate; Vinegar naphtha.
Fair Lawn, NJ
For information, call: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 -
Composition, Information on Ingredients
Symbols: XI F
Risk Phrases: 11 36 66 67
Section 3 - Hazards
Appearance: clear, colorless liquid. Flash Point: -4 deg C. May cause
respiratory tract irritation. Warning! Flammable liquid
and vapor. Causes eye irritation. Prolonged or repeated contact causes
defatting of the skin with irritation, dryness, and cracking. Breathing vapors
may cause drowsiness and dizziness.
Target Organs: Central
nervous system, respiratory system, eyes, skin.
Eye: Causes eye irritation. Vapors may
cause eye irritation.
Skin: May cause skin irritation.
Repeated or prolonged exposure may cause drying and cracking of the skin. The
majority of human studies have demonstrated that ethyl acetate doe s not cause
an allergic response on human skin. However, there is one case report of a woman
developing a skin allergy to ethyl acetate.
cause irritation of the digestive tract. Ingestion of large amounts may cause
central nervous depression. May cause headache, nausea, fatigue, and dizziness.
These effects may be caused in part by ethanol which is released when ethyl
acetate is broken down in the body.
Inhalation: May cause
respiratory tract irritation. May be harmful if inhaled. Inhalation of high
concentrations may cause narcotic effects.
inhalation may cause effects similar to those of acute inhalation. Animals
exposed to 4300 ppm (mice) and 2000 ppm (guinea pig), 6 hours/ day for 7 days
developed minor blood changes & loss of appetite. There was no indication of
liver or kidney injury. Rabbits exposed to 16000 mg/m3 (4440 ppm), 1 hour/day
for 40 days developed secondary anemia ( decreased number of red blood cells),
decreased hemoglobin levels, inc reased numbers of macrophages, congestion and
fatty degeneration of va rious organs, and enlargement of the spleen. A reviewer
suggested that the organ damage may have been due to impurities present in the
Section 4 - First Aid
Eyes: In case of contact, immediately flush eyes
with plenty of water for at least 15 minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water.
Remove contaminated clothing and shoes. Get medical aid if irritation develops
and persists. Wash clothing before reuse.
swallowed, do not induce vomiting unless directed to do so by medical personnel.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: If inhaled, remove to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician: Treat symptomatically
Section 5 - Fire
Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Vapors may form an explosive mixture with air. During a fire, irritating
and highly toxic gases may be generated by thermal decomposition or combustion.
Use water spray to keep fire-exposed containers cool. Flammable liquid and
vapor. Vapors are heavier than air and may travel to a source of ignition and
flash back. Vapors can spread along the ground and collect in low or confined
Extinguishing Media: Water may be ineffective. Use
water spray, alcohol foam, CO2, dry chemical.
Flash Point: -4 deg C (
24.80 deg F)
Autoignition Temperature: 426 deg C ( 798.80 deg F)
Explosion Limits, Lower:2.0
Rating: (estimated) Health: 1; Flammability: 3; Instability: 0
Section 6 -
Accidental Release Measures
Information: Use proper personal protective equipment as indicated in
Spills/Leaks: Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately, observing
precautions in the Protective Equipment section. Remove all sources of ignition.
Absorb spill using an absorbent, non-combustible material such as earth, sand,
or vermiculite. Do not use combustible materials such as saw dust. Provide
ventilation. Use only non-sparking tools and equipment.
Section 7 - Handling
Handling: Wash thoroughly after handling. Ground and
bond containers when transferring material. Avoid contact with eyes, skin, and
clothing. Empty containers retain product residue, (liquid and/or vapor), and
can be dangerous. Keep container tightly closed. Do not pressurize, cut, weld,
braze, solder, drill, grind, or expose empty containers to heat, sparks or open
flames. Use only with adequate ventilation. Keep away from heat, sparks and
flame. Avoid breathing vapor or mist.
Storage: Keep away
from heat, sparks, and flame. Keep away from sources of ignition. Store in a
tightly closed container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Flammables-area.
Section 8 - Exposure
Controls, Personal Protection
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate general or
local explosion-proof ventilation to keep airborne levels to acceptable levels.
||400 ppm TWA
||400 ppm TWA; 1400 mg/m3 TWA 2000 ppm IDLH
||400 ppm TWA; 1400 mg/m3
OSHA Vacated PELs: Ethyl
acetate: 400 ppm TWA; 1400 mg/m3 TWA
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin
Clothing: Wear appropriate protective clothing to
prevent skin exposure.
Respirators: Follow the OSHA respirator
regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - Physical
and Chemical Properties
Appearance: clear, colorless
Odor: sweet, fruity
pH: Not available.
Vapor Pressure: 73 mm Hg @ 20 deg
Vapor Density: 3.04 (Air=1)
Evaporation Rate:6.2 (Butyl
Viscosity: 0.44 cps @ 25 deg C
77 deg C
Freezing/Melting Point:-83 deg C
Solubility: Slightly soluble.
Specific Gravity/Density:0.9 (Water=1)
Section 10 -
Stability and Reactivity
Stability: Stable at room temperature in closed containers under normal
storage and handling conditions.
Conditions to Avoid: Ignition
sources, moisture, excess heat, attacks some plastics, rubber, and coatings,
Incompatibilities with Other Materials: Strong
oxidizing agents, strong acids, strong bases.
Products: Carbon monoxide, carbon dioxide, ethyl alcohol, acetic acid.
Hazardous Polymerization: Will not occur.
Section 11 -
CAS# 141-78-6: AH5425000
Inhalation, mouse: LC50 = 45 gm/m3/2H;
Inhalation, rat: LC50 =
Oral, mouse: LD50 = 4100 mg/kg;
Oral, rabbit: LD50 = 4935
Oral, rat: LD50 = 5620 mg/kg;
Skin, rabbit: LD50 = >20
CAS# 141-78-6: Not listed by
ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Cytogenetic Analysis: hamster fibroblast 9g/L Sex Chromosome
Loss/Non-disjunction: S. cerevisiae 24400 ppm.
Other Studies: See
actual entry in RTECS for complete information.
Section 12 -
Fish: Fathead Minnow: 230mg/L; 96H; Daphnid LC50=2500 mg/L/96H Golden orfe
Environmental: Terrestrial: Expected to have high
mobility in soil. Volatilization of ethyl acetate from moist soil surfaces is
expected to be important. Aquatic: Not expected to adsorb to suspended solids
and sediment in water. Atmospheric: Expected to exist solely as a vapor in the
ambient atmosphere. Vapor-phase ethyl acetate is degraded in the atmosphere by
reaction with photochemically-produced hydroxyl radicals; the half-life for this
reaction in air is estimated to be 10 days.
biodegrades at a high rate with little bioconcentration.
Section 13 - Disposal
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 141-78-6:
waste number U112 (Ignitable waste).
Section 14 -
Section 15 -
CAS# 141-78-6 is listed on the TSCA
Health & Safety Reporting List
None of the
chemicals are on the Health & Safety Reporting List.
None of the chemicals in this product are under a Chemical Test
CAS# 141-78-6: 4/12b
TSCA Significant New
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding
CAS# 141-78-6: 5000 lb final RQ; 2270 kg final RQ
302 Extremely Hazardous Substances
None of the chemicals in this product
have a TPQ.
CAS # 141-78-6: flammable.
No chemicals are reportable under Section 313.
This material does not contain any hazardous air pollutants. This
material does not contain any Class 1 Ozone depletors. This material does not
contain any Class 2 Ozone depletors.
Clean Water Act:
None of the
chemicals in this product are listed as Hazardous Substances under the CWA. None
of the chemicals in this product are listed as Priority Pollutants under the
CWA. None of the chemicals in this product are listed as Toxic Pollutants under
None of the chemicals in this product are
considered highly hazardous by OSHA.
CAS# 141-78-6 can be
found on the following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk
Level: None of the chemicals in this product are listed.
Labeling in Accordance with EC Directives
R 11 Highly flammable.
R 36 Irritating to eyes.
R 66 Repeated exposure may cause skin dryness or
Vapors may cause drowsiness and dizziness.
16 Keep away from sources of ignition - No
S 26 In case of
contact with eyes, rinse immediately
with plenty of water and seek medical
S 33 Take precautionary measures against static
WGK (Water Danger/Protection)
CAS# 141-78-6: 1
CAS# 141-78-6 is listed on Canada's DSL List.
This product has a WHMIS classification of B2.
Ingredient Disclosure List
CAS# 141-78-6 is listed on the Canadian
Ingredient Disclosure List.
OEL-AUSTRALIA:TWA 400 ppm (1400 mg/m3) OEL-BELGIUM:T
WA 400 ppm (1440 mg/m3)
OEL-CZECHOSLOVAKIA:TWA 400 mg/m3;STEL 2000 mg
/m3 OEL-DENMARK:TWA 300 ppm
(1100 mg/m3) OEL-FINLAND:TWA 300 ppm (11
00 mg/m3);STEL 500 ppm (1800 mg/m3)
OEL-FRANCE:TWA 400 ppm (1400 mg/m
3) OEL-GERMANY:TWA 400 ppm (1400 mg/m3)
OEL-HUNGARY:TWA 400 mg/m3;ST
EL 1200 mg/m3 OEL-JAPAN:TWA 400 ppm (1400 mg/m3)
:TWA 400 ppm (1400 mg/m3) JAN9 OEL-THE PHILIPPINES:TWA
400 ppm (1400
mg/m3) JAN9 OEL-POLAND:TWA 200 ppm OEL-RUSSIA:TWA 400 ppm;STEL
g/m3 OEL-SWEDEN:TWA 150 ppm (500 mg/m3);STEL 300 ppm (1100 mg/m3)
L-SWITZERLAND:TWA 400 ppm (1400 mg/m3);STEL 800 ppm OEL-TURKEY:TWA 40
ppm (1400 mg/m3) OEL-UNITED KINGDOM:TWA 400 ppm (1400 mg/m3) OEL I
BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAN
SINGAPORE, VIETNAM check ACGI TLV
Section 16 -
MSDS Creation Date:
Revision #7 Date: 7/11/2003
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
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