Material Safety Data
Section 1 - Chemical Product and Company
MSDS Name: Dichloromethane
Catalog Numbers: S80084, S80084-1, S80084-2SPEC,
S80084HPLC, S80084SPEC, 23FD37500, BP1186-4, BP1186POP19, BP1186POP20,
BP1186POP50, BP1186SS-19, BP1186SS-200, BP1186SS-28, BP1186SS-50, BP2608-100,
D1381, D1384, D138SK4, D142-4, D142POP19, D142POP200, D142POP50, D142RS-19,
D142RS115, D142RS200, D142RS28, D142RS50, D142SS-115, D142SS-200, D142SS-28,
D142SS-50, D142SS19, D143-1, D143-4, D143J1, D143N219, D143NB219, D143POP19,
D143POP200, D143POP28, D143POP50, D143POPN19, D143RS-19, D143RS115, D143RS200,
D143RS28, D143RS50, D143SK-1, D143SK-4, D143SS-115, D143SS-200, D143SS-28,
D143SS-50, D143SS19, D149-1, D149POP19, D149POP200, D149POP50, D149RS-19,
D149RS-200, D149RS-50, D149SS19, D149SS200, D149SS50, D150-1, D150-4, D150J-4,
D150SK-1, D150SK-4, D151-1, D151-4, D151POP19, D151POP200, D151POP50, D151RS-19,
D151RS-200, D151RS-28, D151RS-50, D151RS115, D151SS-115, D151SS-200, D151SS-28,
D151SS-50, D151SS19, D154-4, D1544LC, D35-1, D35-4, D37-1, D37-20, D37-200,
D37-4, D37-500, D37200LC, D37FB-115, D37FB-19, D37FB-200, D37FB-50, D37POP19,
D37POP200, D37POP50, D37POPB19, D37POPB200, D37POPB50, D37RB-115, D37RB-19,
D37RB-200, D37RB-50, D37RS-115, D37RS-200, D37RS-28, D37RS-50, D37RS19, D37SK-4,
D37SS-115, D37SS-200, D37SS-28, D37SS-50, D37SS19, NC9905243, NC9964976
Synonyms: Methylene chloride; Methane dichloride; Methylene
bichloride; Methylene dichloride; Dichloromethane; DCM.
Fair Lawn, NJ 07410
For information, call: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
International CHEMTREC assistance, call: 703-527-3887
Section 2 -
Composition, Information on Ingredients
Risk Phrases: 40
Section 3 - Hazards
Appearance: colorless liquid. This substance has caused adverse reproductive
and fetal effects in animals. Potential cancer hazard.
Warning! Causes eye and skin irritation. Causes respiratory tract
irritation. Harmful if swallowed. May be harmful if inhaled. May cause central
nervous system effects. Methylene chloride is metabolically converted to carbon
monoxide after systemic absorption, which yields increased concentrations of
carboxyhemoglobin in the blood. May cause kidney damage.
Organs: Blood, kidneys, heart, central nervous system, liver, lungs,
Potential Health Effects
Eye: Contact with eyes may cause severe irritation,
and possible eye burns.
Skin: May be absorbed through the
skin. Causes irritation with burning pain, itching, and redness. Prolonged
exposure may result in skin burns.
gastrointestinal irritation with nausea, vomiting and diarrhea. May cause kidney
damage. May cause central nervous system depression, characterized by
excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced
stages may cause collapse, unconsciousness, coma and possible death due to
respiratory failure. May cause carboxyhemoglobinemia.
Inhalation: Inhalation of high concentrations may cause
central nervous system effects characterized by nausea, headache, dizziness,
unconsciousness and coma. Causes respiratory tract irritation. May cause
narcotic effects in high concentration. Vapors may cause dizziness or
suffocation. May cause blood changes. Overexposure may cause an increase in
carboxyhemoglobin levels in the blood. Can produce delayed pulmonary edema.
Because of its high volatility, airborne concentrations of methylene c hloride
can accumulate in poorly ventilated areas. Odor is a poor indi cator of possibly
dangerous air concentrations of methylene chloride.
Chronic: Possible cancer hazard based on tests with
laboratory animals. Prolonged or repeated skin contact may cause dermatitis. May
cause reproductive and fetal effects. Laboratory experiments have resulted in
mutagenic effects. Chronic exposure may cause lung, liver, and pancreatic
tumors. May cause conjunctivitis and/or corneal burns.
Section 4 - First Aid
Eyes: In case of contact, immediately flush eyes
with plenty of water for at least 15 minutes. Get medical aid.
Skin: In case of contact, flush skin with plenty of water.
Remove contaminated clothing and shoes. Get medical aid if irritation develops
and persists. Wash clothing before reuse.
swallowed, do not induce vomiting unless directed to do so by medical personnel.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: If inhaled, remove to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician: Treat symptomatically
Section 5 - Fire
Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Use water spray to keep fire-exposed containers cool. No flash point in
conventional closed tester, but forms flammable vapor-air mixtures in larger
volumes and may be an explosion hazard in a confined space.
Extinguishing Media: Use water spray, dry chemical, carbon
dioxide, or appropriate foam.
Flash Point: Not applicable.
Autoignition Temperature: 556 deg C ( 1,032.80 deg F)
Explosion Limits, Lower:13 vol %
Upper: 23 vol %
NFPA Rating: (estimated) Health: 2; Flammability: 1;
Section 6 -
Accidental Release Measures
Information: Use proper personal protective equipment as indicated in
Spills/Leaks: Absorb spill with inert material
(e.g. vermiculite, sand or earth), then place in suitable container. Avoid
runoff into storm sewers and ditches which lead to waterways. Clean up spills
immediately, observing precautions in the Protective Equipment section. Remove
all sources of ignition. Provide ventilation.
Section 7 - Handling
Handling: Wash thoroughly after handling. Remove
contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and
clothing. Keep container tightly closed. Avoid contact with heat, sparks and
flame. Use only with adequate ventilation. Avoid breathing vapor or mist.
Storage: Store in a tightly closed container. Keep from
contact with oxidizing materials. Store in a cool, dry, well-ventilated area
away from incompatible substances. Store below 40°C. Keep away from active
Section 8 - Exposure
Controls, Personal Protection
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the permissible
||50 ppm TWA
||2300 ppm IDLH
||25 ppm TWA (8 hr.); 125 ppm STEL (15 min.);
12.5 ppm Action Level (see 29 CFR 19
OSHA Vacated PELs:
Methylene chloride: 500 ppm TWA
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin
Clothing: Wear appropriate protective clothing to
prevent skin exposure.
Respirators: A respiratory protection program
that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace conditions warrant a
Section 9 - Physical
and Chemical Properties
Odor: ethereal odor -
pH: Not available.
Vapor Pressure: 350 mm
Hg @ 20 deg C
Vapor Density: 2.93 (Air=1)
Viscosity: Not available.
Point: 40 deg C
Freezing/Melting Point:-97 deg C
Decomposition Temperature:Not available.
Specific Gravity/Density:1.33 (Water=1)
Section 10 -
Stability and Reactivity
Stability: Stable at room temperature in closed containers under normal
storage and handling conditions. May form explosive mixtures in atmospheres
having high oxygen content.
Conditions to Avoid: Excess heat, attacks
some plastics, rubber, and coatings, confined spaces, When no water is present,
dichloromethane is not corrosive to metals. At high temperatures and in the
presence of water (causing slow decomposition forming HCl), corrosion of iron,
some stainless steels, copper and aluminum can occur..
with Other Materials: Strong oxidizing agents, strong bases, chemically
Hazardous Decomposition Products: Hydrogen chloride,
phosgene, carbon monoxide, carbon dioxide.
Will not occur.
Section 11 -
CAS# 75-09-2: PA8050000
Draize test, rabbit, eye: 162 mg Moderate;
Draize test, rabbit,
eye: 10 mg Mild;
Draize test, rabbit, eye: 500 mg/24H Mild;
rabbit, skin: 810 mg/24H Severe;
Draize test, rabbit, skin: 100 mg/24H
Inhalation, mouse: LC50 = 14400 ppm/7H;
Inhalation, rat: LC50 =
Oral, mouse: LD50 = 873 mg/kg;
Oral, rat: LD50 = 1600
- Animal Carcinogen
California: carcinogen; initial date 4/1/88
NIOSH: potential occupational carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2B
Epidemiology: There are few reports of injury despite
widespread use of dichloromethane (ACGIH, 1991). Solvent abuse has led to death
Teratogenicity: Inhalation, rat: TCLo = 4500
ppm/24H (female 1-17 day(s) after conception) Effects on Newborn - behavioral.;
Inhalation, rat: TCLo = 1250 ppm/7H (female 6-15 day(s) after conception)
Specific Developmental Abnormalities - musculoskeletal system and urogenital
Reproductive Effects: Reproductive effects have occurred in
Neurotoxicity: No information available.
Mutagenicity: DNA inhibition: Human, Fibroblast = 5000 ppm/1H
(Continuous).; Morphological transformation: Rat, Embryo = 160 umol/L.; DNA
damage: Oral, rat = 1275 mg/kg.; Inhalation, mouse: TCLo = 2000 ppm/5H/2Y-C
(Tumorigenic - Carcinogenic by RTECS criteria--Lungs, Thorax, or Respiration -
Other Studies: See actual entry in RTECS for complete
Section 12 -
Fish: Bluegill/Sunfish: 230mg/L; 24H; Static Fathead Minnow: 196mg/L; 96H; This
chemical has a moderate potential to affect some aquatic organisms. It is
resistant to biodegradation, and has a low potential to persist in the aquatic
environment. 96-hr. EC50 (loss of equilibrium); Fathead minnow: 99mg/L; 96-hr.
EC10: 66.3 mg/L. Bluegill sunfish: 96-hr. LC50=220 mg/L; Water flea: 24-hr.
LC50=2270 mg/L; No observed effect level:1550 mg/L.
Terrestrial: Expected to evaporate from near surface soil into the atmosphere;
expected to leach. Aquatic: Primarily lost by evaporation to the atmosphere
which should take several hours depending on wind and mixing conditions.
Atmospheric: Will degrade by reaction with hydroxyl radicals with a half life of
several months. . Dichloromethane is reported to completely biodegrade under
aerobic conditions with sewage seed or activated sludge between 6 hours to 7
days. Not expected to bioconcentrate due to its low octanol/water coefficient.
Physical: No information available.
Other: No information
Section 13 - Disposal
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 75-09-2:
waste number U080.
Section 14 -
Section 15 -
CAS# 75-09-2 is listed on the TSCA
Health & Safety Reporting List
Effective Date: 10/4/82; Sunset Date: 10/4/92
None of the chemicals in this product are under a Chemical Test
None of the chemicals are listed under TSCA
TSCA Significant New Use Rule
None of the chemicals
in this material have a SNUR under TSCA.
Hazardous Substances and corresponding RQs
CAS# 75-09-2: 1000 lb final
RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous
None of the chemicals in this product have a TPQ.
CAS # 75-09-2: acute, chronic.
material contains Methylene chloride (CAS# 75-09-2, 99 5%),which is subject to
the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 75-09-2 is listed as a hazardous air pollutant
(HAP). This material does not contain any Class 1 Ozone depletors. This material
does not contain any Class 2 Ozone depletors.
None of the chemicals in this product are listed as Hazardous
Substances under the CWA. CAS# 75-09-2 is listed as a Priority Pollutant under
the Clean Water Act. CAS# 75-09-2 is listed as a Toxic Pollutant under the Clean
None of the chemicals in this product are
considered highly hazardous by OSHA.
CAS# 75-09-2 can be
found on the following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, Massachusetts.
The following statement(s)
is(are) made in order to comply with the California Safe Drinking Water Act:
WARNING: This product contains Methylene chloride, a chemical known to the state
of California to cause cancer. California No Significant Risk Level: CAS#
75-09-2: 200 ug/day NSRL (inhalation); 50 ug/day NSRL (except inhalation)
Labeling in Accordance with EC Directives
R 40 Limited evidence of a carcinogenic effect.
S 23 Do not inhale gas/fumes/vapour/spray.
S 24/25 Avoid contact with skin and eyes.
S 36/37 Wear suitable
protective clothing and
CAS# 75-09-2: 2
Canada - DSL/NDSL
75-09-2 is listed on Canada's DSL List.
Canada - WHMIS
product has a WHMIS classification of D1B, D2A.
CAS# 75-09-2 is listed on the Canadian Ingredient
CAS# 75-09-2: OEL-AUSTRALIA:TWA
100 ppm (350 mg/m3);Carcinogen OEL-
AUSTRIA:TWA 100 ppm (360 mg/m3)
OEL-BELGIUM:TWA 50 ppm (174 mg/m3);Ca
rcinogen OEL-CZECHOSLOVAKIA:TWA 500
mg/m3;STEL 2500 mg/m3 OEL-DENMAR
K:TWA 50 ppm (175 mg/m3);Skin;Carcinoge
OEL-FINLAND:TWA 100 ppm (350
mg/m3);STEL 250 ppm (870 mg/m3) OEL-FRANCE:TWA
100 ppm (360 mg/m3);ST
EL 500 ppm (1800 mg/m3) OEL-GERMANY:TWA 100 ppm (360
n OEL-HUNGARY:STEL 10 mg/m3;Carcinogen OEL-JAPAN:TWA 100 ppm
/m3) OEL-THE NETHERLANDS:TWA 100 ppm (350 mg/m3);STEL 500 ppm
E PHILIPINES:TWA 500 ppm (1740 mg/m3) OEL-POLAND:TWA 50 mg/m3
SSIA:TWA 100 ppm;STEL 50 mg/m3 OEL-SWEDEN:TWA 35 ppm (120
70 ppm (25 mg/m3);Skin OEL-SWITZERLAND:TWA 100 ppm (360
500 ppm OEL-THAILAND:TWA 500 mg/m3;STEL 1000 mg/m3
0 ppm (1740 mg/m3) OEL-UNITED KINGDOM:TWA 100 ppm (350
0 ppm OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
N NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 -
MSDS Creation Date:
Revision #5 Date: 2/20/2003
The information above is
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