Surface-Immobilized Enzyme -- Effectiveness Factor

Biochemical Engineering


Problem Statement: Consider an enzyme that is immobilized on the surface of the support material. Given the substrate concentration in the bulk is sb, find the substrate concentration on the surface in the presence of mass transfer resistance. Find the rate of reaction. Find the effectiveness factor h, which is the ratio of the observed reaction rate with mass transfer resistance to the rate without mass transfer resistance. How does the effectiveness factor depend on the Damkohler number, which is the ratio of maximum rate of reaction vm to the maximum rate of mass transfer kl*sb? How does the apparent rate of reaction depend on the bulk substrate concentration sb for different values of the mass transfer coefficient kl?

Solution:

Surface-Immobilized Enzyme -- Effectiveness Factor & Apparent Reaction Rate


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Biochemical Engineering -- Surface-Immobilized Enzyme -- Effectiveness Factor
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