Nam Sun Wang
's ...
ENCH482
Biochemical Engineering
Spring 2013
Class Handouts & Lecture Notes
Class Syllabus
Policy on Academic Integrity
Homework
1/23 syllabus, terminology, Chemical Engineering vs. Biochemical Engineering
1/25 brief History, Applications, Nomenclature, Classification, Kingdom of Protists, species
1/28 Prokaryotes/Eukaryotes, Virus, Bacteria, Yeasts
NCBI (National Center for Biotechnology Information)
, Taxanomy
1/30 Biochemistry (Carbohydrates, Lipids, Amino Acid, Protein, RNA/DNA)
2/04 Enzymes, Michaelis-Menten kinetics
2/06 Michaelis-Menten Kinetics, ODE for batch, fed-batch, CSTR
2/08 Integrate ODEs arising from Enzyme Kinetic Mechanisms
2/11 Michaelis-Menten Kinetics (manual reduction to v), solution of ODEs
2/13 Inhibition (competitive, non-competitive, un-competitive)
2/15 Substrate inhibition
2/18 pH effect, temperature effect
2/20 Enzyme immobilization, catalyst support & devices, surface/external mass transfer
2/22 Enzyme immobilization, gels, internal mass transfer
2/25 Bioreactors with immobilized enzymes (batch, fed-batch, CSTR)
2/27 Central Dogma of Biology, DNA replication
3/01
Quiz #1
3/04 PCR, transcription
3/06 snow
3/08 transcription, translation
codons
3/11 insulin, cloning
3/13 cloning
3/15 cloning
3/18-3/22 Spring break
3/25 metabolism (redox, NADH, ATP)
3/27 matabolic pathways (Andrew Quinn)
3/29 metabolic engineering, isoprene example (Andrew Quinn)
4/01 cell growth
4/03 biomass measurement
4/05
Quiz #2
4/08 cell growth, substrte utilization, & product formation, BSF tour
4/10 batch, fed-batch, CSTR, bioreactor dynamics
4/12 CSTR, washout dilution, max productivity
4/15 penicillin video
4/17 mode of bioreactor operation for various bioproducts
4/19 stoichiometry
4/22 beer fermentation
4/24 cell recycle
4/26 immobilized cells, multiple bioreactors
4/29 oxygen mass transfer
5/01 purification
5/03 purification
5/06 segregated model
5/08 mixed culture
5/14 8am-10am
Final Examination
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Biochemical Engineering
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Nam Sun Wang
Department of Chemical & Biomolecular Engineering
University of Maryland
College Park, MD 20742-2111
301-405-1910 (voice)
301-314-9126 (FAX)
e-mail:
nsw@umd.edu
©2013 by Nam Sun Wang
