dterm mHEAD> BCHM 461 - Introductory BioChemistry - Dr. Fushman
 

Biochemistry: BCHM 461

Fall 2019

Course meets in Chem 1402, MW 4:00-5:15 pm
Professor: David Fushman
Office: Room 1121 Biomolecular Sciences Bldg (#296)
Office Hours: Tuesday 12:30 - 2:30 pm
E-mail: fushman@umd.edu

Syllabus

Textbooks

Required:
Lehninger Principles of Biochemistry, 7th edition by Nelson and Cox
Recommended:
The Absolute, Ultimate Guide to Lehninger Principles of Biochemistry, 7th edition by Osgood and Ocorr
Biochemistry by Voet and Voet
 
Assignments:
Reading and problem assignments are from Lehninger Principles of Biochemistry
Date Reading Problems Q&A
11/20 Midterm Exam #2    
11/18 Ch.6.3: pp 198-206 Ch.6: Problems 8-13, 15. Worked examples 6-1, 6-2 in Ch. 6.3. Prepare for the midterm exam.  
11/13 Ch.6.2: pp 189-198 Ch.6: Problems 1-4,7. Solutions to practice problems from a previous midterm exam #2 are here. I strongly sugest that you look at these solutions only after you attempted to solve the problems yourself. Review session: Mon Nov 18, right after the lecture. Bring your questions. 
11/11 Ch.6.1-6.2: pp 187-198 Ch.6: Problems 1-4,7.    
11/06 Ch.5.1: pp 163-174 (read this sub-chapter to the end) Ch.5: Problems 2,3,7,9. Graded Quiz #4 due on Wednesday Nov 13) is here. Practice problems from a previous midterm exam #2 are here. 
11/04 Ch.5.1: pp 158-162 Ch.5: Problem 6  
10/30 Ch.5.1: pp 157, 160-161 + Lecture notes. The lecture notes have been updated. Ch.5: Problems 1,4,5. Here is your graded Quiz #3. It is due by 3:30 pm on Wednesday Nov 6.  
10/28 Lecture slides/notes on NMR. Watch youtube videos listed on slide #7.  Answers to Exam #1 problems and scores statistics are posted below.
10/23 Ch.4, Box 4-5 + lecture notes on X-ray crystallography, small-angle scattering, and cryo-EM    
10/21 Ch.4: pp 125, Box 4-5 + lecture slides    
10/16 Ch.4.4: pp 142-151 + lecture slides Ch.4: Problem 14. Refresh your knowledge of basic trigonometric functions: sine and cosine.    
10/14 Ch.4.3: pp 125-133, 137-142 (skip box 4-5 for now) PyMOL-related homework questions on slide 1 of the lecture  
10/09 Slides and video recordings for Lecture 12 parts 1 and 2 are available on ELMS Homework assignments are in the PyMOL lecture slides.    
10/07 Midterm Exam #1    
10/02 Ch.4.2 pp. 119-125. Prepare for the upcoming midterm exam. Ch.4: Problems 2-4,10,13. Solutions to Practice problems from a previous midterm exam #1 are here.  
09/30 Ch.3.4, pp. 96-109; Ch.4.1, pp. 115-119. Ch.3: Problems 18-20,23. Ch.4: Problem 1. + Homework problems from the lecture slides.  Review session for the upcoming exam will take place after class on Wednesday. Bring your questions.
09/25 Ch.3.3 pp 93-96; Ch 3.4 pp. 100-102; Ch 3.1 Box 3-1 Homework questions/problems in the lecture slides. Practice problems from a previous midterm exam #1 are here..  
09/23 Ch.3.3, pp. 89-96 Ch.3, Problems 16,17,22  
09/18 Ch.3.1, pp.81-85, Ch. 3.2: pp.85-89 Ch.3, Problems: 2-4, 11-14. Here is your graded Quiz #2. It is due by 3:30 pm on Wednesday Sept 25.  
09/16 Ch.3.1, pp. 75-81 Ch.3, Problems 1,7  
09/13 Ch.2: read to the end Ch.2, Problems: 11-14,16,18-22,24-30; answer questions on lecture slides 12, 20, and 26. A detailed derivation of the equation for the pH problem considered in class is here.
09/09 Ch.2.1, 2.2 pp. 58-61 (till weak acids) Ch.2, Problems: 2,3,5-8. .
09/04 Ch. 2.1, pp: 45-58; Finish Bioenergetics: Ch. 1.3,13.1. Ch.2, p.71, Pr. 1. Your first Quiz (due on Sept 9, 2019 at 3:30pm) is here.  
08/28 Ch.1.2-1.3 (pp.20-27); Ch.13.1 (pp.505-511) Ch.13: pp.538-539, Problems #2-5. Also Homework Problems I-III and Questions in Lecture_2 slides (ELMS) -- these problems can also be found here.  
08/26 Ch.1, pp. 1-12(covered in class)-20 Ch.1: Problems: 3,7,9; Figure 1-16: refresh your memory of the chemical properties of the functional groups shown in that figure. PDF version of the lecture slides can be found here
Exam # 1: Exam # 2: Final Exam:
Statistics Statistics Statistics
Solutions Solutions Solutions
     

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