dterm mHEAD> BCHM 461 - Introductory BioChemistry - Dr. Fushman

Biochemistry: BCHM 461

Fall 2019

Course meets in Chem 1402, MW 4:00-5:15 pm
Professor: David Fushman
Office: Room 1121 Biomolecular Sciences Bldg (#296)
Office Hours: Tuesday 12:30 - 2:30 pm
E-mail: fushman@umd.edu



Lehninger Principles of Biochemistry, 7th edition by Nelson and Cox
The Absolute, Ultimate Guide to Lehninger Principles of Biochemistry, 7th edition by Osgood and Ocorr
Biochemistry by Voet and Voet
Reading and problem assignments are from Lehninger Principles of Biochemistry
Date Reading Problems Q&A
11/20 Midterm Exam #2    
11/18 Ch.6.3: pp 198-206 Ch.6: Problems 8-13, 15. Worked examples 6-1, 6-2 in Ch. 6.3. Prepare for the midterm exam.  
11/13 Ch.6.2: pp 189-198 Ch.6: Problems 1-4,7. Solutions to practice problems from a previous midterm exam #2 are here. I strongly sugest that you look at these solutions only after you attempted to solve the problems yourself. Review session: Mon Nov 18, right after the lecture. Bring your questions. 
11/11 Ch.6.1-6.2: pp 187-198 Ch.6: Problems 1-4,7.    
11/06 Ch.5.1: pp 163-174 (read this sub-chapter to the end) Ch.5: Problems 2,3,7,9. Graded Quiz #4 due on Wednesday Nov 13) is here. Practice problems from a previous midterm exam #2 are here. 
11/04 Ch.5.1: pp 158-162 Ch.5: Problem 6  
10/30 Ch.5.1: pp 157, 160-161 + Lecture notes. The lecture notes have been updated. Ch.5: Problems 1,4,5. Here is your graded Quiz #3. It is due by 3:30 pm on Wednesday Nov 6.  
10/28 Lecture slides/notes on NMR. Watch youtube videos listed on slide #7.  Answers to Exam #1 problems and scores statistics are posted below.
10/23 Ch.4, Box 4-5 + lecture notes on X-ray crystallography, small-angle scattering, and cryo-EM    
10/21 Ch.4: pp 125, Box 4-5 + lecture slides    
10/16 Ch.4.4: pp 142-151 + lecture slides Ch.4: Problem 14. Refresh your knowledge of basic trigonometric functions: sine and cosine.    
10/14 Ch.4.3: pp 125-133, 137-142 (skip box 4-5 for now) PyMOL-related homework questions on slide 1 of the lecture  
10/09 Slides and video recordings for Lecture 12 parts 1 and 2 are available on ELMS Homework assignments are in the PyMOL lecture slides.    
10/07 Midterm Exam #1    
10/02 Ch.4.2 pp. 119-125. Prepare for the upcoming midterm exam. Ch.4: Problems 2-4,10,13. Solutions to Practice problems from a previous midterm exam #1 are here.  
09/30 Ch.3.4, pp. 96-109; Ch.4.1, pp. 115-119. Ch.3: Problems 18-20,23. Ch.4: Problem 1. + Homework problems from the lecture slides.  Review session for the upcoming exam will take place after class on Wednesday. Bring your questions.
09/25 Ch.3.3 pp 93-96; Ch 3.4 pp. 100-102; Ch 3.1 Box 3-1 Homework questions/problems in the lecture slides. Practice problems from a previous midterm exam #1 are here..  
09/23 Ch.3.3, pp. 89-96 Ch.3, Problems 16,17,22  
09/18 Ch.3.1, pp.81-85, Ch. 3.2: pp.85-89 Ch.3, Problems: 2-4, 11-14. Here is your graded Quiz #2. It is due by 3:30 pm on Wednesday Sept 25.  
09/16 Ch.3.1, pp. 75-81 Ch.3, Problems 1,7  
09/13 Ch.2: read to the end Ch.2, Problems: 11-14,16,18-22,24-30; answer questions on lecture slides 12, 20, and 26. A detailed derivation of the equation for the pH problem considered in class is here.
09/09 Ch.2.1, 2.2 pp. 58-61 (till weak acids) Ch.2, Problems: 2,3,5-8. .
09/04 Ch. 2.1, pp: 45-58; Finish Bioenergetics: Ch. 1.3,13.1. Ch.2, p.71, Pr. 1. Your first Quiz (due on Sept 9, 2019 at 3:30pm) is here.  
08/28 Ch.1.2-1.3 (pp.20-27); Ch.13.1 (pp.505-511) Ch.13: pp.538-539, Problems #2-5. Also Homework Problems I-III and Questions in Lecture_2 slides (ELMS) -- these problems can also be found here.  
08/26 Ch.1, pp. 1-12(covered in class)-20 Ch.1: Problems: 3,7,9; Figure 1-16: refresh your memory of the chemical properties of the functional groups shown in that figure. PDF version of the lecture slides can be found here
Exam # 1: Exam # 2: Final Exam:
Statistics Statistics Statistics
Solutions Solutions Solutions

Link to UMD CANVAS website

Link to Fushman Lab homepage