Physical BioChemistry: BCHM 485

Spring 2010

Course meets in Chem 2201, TuTh 9:30 am
Professor: David Fushman
Office: Room 1121 Biomolecular Sciences Bldg (#296)
Office Hours: Wednesday, 12:30 - 2 pm
E-mail: fushman@umd.edu

Syllabus

Textbooks

Required:
Quantum Chemistry & Spectroscopy by Thomas Engel
Thermodynamics, Statistical Thermodynamics, and Kinetics by Thomas Engel & Philip Reid
Recommended:
Physical Chemistry by Peter Atkins and Julio de Paula, 8-th edition, Vol.2 Quantum Chemistry, Spectroscopy, and Statistical Thermodynamics;
Physical Chemistry with Applications to the Life Sciences by David Eisenberg and Donald Crothers;
Principles of Physical Biochemistry by van Holde, Johnson & Ho;
Molecular Driving Forces by Dill & Bromberg;
Biophysical Chemistry by Cantor & Schimmel.
 
Assignments:
Reading and problems are either from Quantum Chemistry & Spectroscopy [QCS] or from Thermodynamics, Statistical Thermodynamics, and Kinetics [TSK]
Date Reading Problems
05/14 Final Exam: Friday, 8:00am(!!!).  
Postings: 1. Don't forget to do the online course evaluation!!!
2. A review session will be held on Wednesday, May 12, 1:00-2:00pm. in our classroom (CHEM 2201). Please do come if you have questions related to the final exam.
The Equations Sheet for your final exam is here.
05/11 Hand-out notes on polymer chain statistics can be found here. Notes on the random walk model that complement the hand-out material can be found here. Preparation for the final exam. Today's material (statistics of polymer chains) will NOT be on the exam. Solutions to HW#4 are here.
05/06 Ch.15: 15.1-15.6 Ch.15: Q: 15.1-15.6,15.8,15.10,15.12; Pr: 15.2,15.3,15.4,15.12,15.28. Exam#2 statistics and the current distribution of scores are posted below.
05/04 Ch.14: 14.1-14.5, 14.6-14.10. Ch.14: Q: 14.1-14.6,14.10-14.12; Pr: 14.1,14.10,14.14,14.18. Your last graded homework (#4, due date: Tue May 11) can be found here.
04/29 Prof. P. Paukstelis on protein structure determination using X-ray diffraction of protein crystals. Solution to Exam #2 problems are posted below.
04/27 Midterm Exam #2 Don't forget to bring a pen/pencil and a calculator!
04/22 Ch.13 Ch.13: Q:13.6,13/8; Pr: 13.6,13.8,13.9,13.11,13.18,13.22,(13.4). Review session: Fri Apr 23 at 3pm in Rm 2118 Biomolec Sci Bldg. Note that the answer to question #2 in HW#3 has been corrected, see here.
04/20 TSK: Ch.12: 12.1-12.3 (probabilities), Ch.13: 13.1-13.5 Ch.13: Q: 13.1-13.5,13.7; Pr: 13.1,13.5,13.12,13.17. Help-sheet with equations for Midterm Exam #2 can be found here.
04/15 Ch.17: 17.12-17.14 Ch.17: Pr: 17.13 + previous assignment (of 04/13); Prove that (alpha+beta) and (alpha-beta) are eigenfunctions of Ix and find the corresponding eigenvalues. Solutions to HW#3 are here.
04/13 Ch.17: 17.1-17.6, 17-11 Ch.17: Q: 17.3,17.14; Pr: 17.3,17.6
04/08 Ch.10: 10.3; Ch.12: 12.1-12.4,12.6,12.8; Ch.13: 13.1-13.2,13.4. Ch.12: Q:12.15;
04/06 Ch.10: 10.1-10.3 (10.4-10.6 optional); Ch.6.2 (Stern-Gerlach) Ch.10: Q:10.7,10.12,10.20. Your next graded Homework (#3) is here. It's due on April 15. Exam #1 score statistics are posted below.
04/01 Ch.9 to the end Ch.9: Q: 9.10,9.12; Example Problems: 9.1-9.6; Pr: 9.4,9.5,9.16,9.25; Show by direct substitution that exp(-ar) is a solution to S.E. when l=0, determine a.
03/30 Ch.8: 8.6,8.8; Ch.9: 9.1-9.3; re-read Ch.3 -- the postulates of QM Ch.9: Q: 9.4,9.7,9.8,9.9; Pr: 9.2,9.8
03/25 Ch.8: 8.4,8.5,8.6 Ch.8: Q: 8.1,8.12; Pr: 8.6,8.7,8.11,8.28. Solutions to Exam #1 problems are posted below.
03/23 Ch.8: 8.1,8.2,8.9 Calculate the amplitude of vibrations for harmonic oscillator (e.g. H2) in the states with n=0,1,2.
03/11 Midterm Exam #1 Don't forget to bring a pen/pencil and a calculator!
03/09 Preparatio for the midterm exam! Finish Ch.7. Ch.8: 8.1-8.3 Ch.8: Q: 8.4; Pr: 8.2,8.9. Evaluate the commutator [lz,lx]
03/04 Ch.7: 7.3-7.5, 7.8 Ch.7: Q: 7.2,7.3,7.9; Pr:7.4,7.6,7.7. Help-sheet with equations for midterm exam #1 can be found here. The review session will take place on Monday March 8, 5-6pm, in Rm 2118 Biomolecular Sciences Bldg (#296). Bring your questions! Solutions to HW#2 are here.
03/02 Ch.7: 7.2,7.7 Ch.7: Q: 7.10; Pr: 7.25. Solutions to HW#1 problems can be found here.
02/25 Ch.7:7.1,7.6 Ch.7: Q: 7.1,7.5,7.14,7.15; Pr: 7.8,7.13,7.14,7.16,7.23; Your second graded homework assignment (due date: Mar.4) can be downloaded from here. We will cover the "particle on a ring" model (Problem 2B) on Tue.
02/23 Ch.6: 6.1,6.3,6.4, (6.5-6.6). The first mid-term exam will be on March 11. Ch6: Q: 6.4,6.6,6.7,6.14,6.15; Pr: 6.3,6.9,6.11,6.16,6.22
02/18 Ch.5: 5.1-5.3,5.5-5.7 Ch.5: Q: 5.6; Pr: 5.1,5.3,5.4
02/16 Ch.4: 4.2-4.4 Ch.4: Q:4.6,4.11; Pr: 4.10,4.12,4.15,4.18,4.19,4.22. Your first graded homework assignment (due date: Feb.25) can be downloaded from here
02/11 Snowday  
02/09 Snowday A sampler of graded homework problems (with answers) from the previous year can be found here.
02/04 Ch.2 (2.3,2.4); Ch.3:3.5; Ch.4: 4.1 Ch.4: Q:4.3-4.5,4.10; Pr: 4.4-4.6,4.13
02/02 Ch.2: 2.4-2.5; Ch.3: 3.4 Ch.2: Q: 2.12,2.14; PR: 2.11,2.19,2.27,2.33,2.35,2.36
01/28 Ch.2: 2.1-2.3; Ch.3: 3.1-3.3 Ch.2: Q: 2.3,2.7,2.9,2.11,2.13,2.15; Pr: 2.3,2.4,2.9,2.12,2.20
01/26 QCS: Ch.1 Questions in the end of Ch.1.
Exam # 1: Exam # 2: Final Exam:
Statistics Statistics Statistics
Solutions Solutions Solutions
     

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