_HEAD> BCHM 485 - Physical BioChemistry - Dr. Fushman
 

Physical BioChemistry: BCHM 485

Spring 2009

Course meets in Chem 2201, TuTh 9:30 am
Professor: David Fushman
Office: Room 1121 Biomolecular Sciences Bldg (#296)
Office Hours: Wednesday, 1:30 - 3 pm
E-mail: fushman@umd.edu

Syllabus

Textbooks

Required:
Quantum Chemistry & Spectroscopy by Thomas Engel
Thermodynamics, Statistical Thermodynamics, and Kinetics by Thomas Engel & Philip Reid
Recommended:
Physical Chemistry by Peter Atkins and Julio de Paula, 8-th edition, Vol.2 Quantum Chemistry, Spectroscopy, and Statistical Thermodynamics;
Physical Chemistry with Applications to the Life Sciences by David Eisenberg and Donald Crothers;
Principles of Physical Biochemistry by van Holde, Johnson & Ho;
Molecular Driving Forces by Dill & Bromberg;
Biophysical Chemistry by Cantor & Schimmel.
 
Assignments:
Reading and problems are either from Quantum Chemistry & Spectroscopy [QCS] or from Thermodynamics, Statistical Thermodynamics, and Kinetics [TSK]
Date Reading Problems
05/15 Final Exam: Friday, 8:00am(!!!).  
Postings: 1. Don't forget to do the online course evaluation!!!
2. If you have questions related to the final exam, please come on Thursday May 14, from 1:30 till 3pm. I will be either in my office or in the seminar room 2118 upstairs.
The Equations Sheet for your final exam is here. It now also includes equations for a polymer chain.
05/12 Preparation to final exam. Solutions to Homework problems #6 can be found here.
05/07 Hand-out notes on helix-coil transition models (2.4 Mb) can be found here. Hand-out derivations and additional material is here. Problems from the hand-out derivations. Solutions to Exam #2 problems can be found here.
05/05 Hand-out notes on polymer chain statistics. Do problems 7-9 from the homework problems set of 04/30.
04/30 Hand-out notes on polymer chain statistics can be found here. Some notes on the random-walk model that complement the hand-out material can be found here. Here are your homework problems. Do problems 1-6.
04/28 Ch.15: 15.1-15.6 Ch.15: Q: 15.1,15.2,15.4-15.6; Pr: 15.1,15.2,15.8. Homework Problem Set #6 (due May 7) can be downloaded from here
04/23 Midterm Exam #2.  
04/21 TSK: Ch.14: 14.1-14.2 Ch.14: Q: 14.1,14.2
04/16 TSK: Ch.14: 14.3-14.8 Ch.14: Q: 14.4-14.8; Pr: 14.1, 14.7, 14.12, 14.16; The formulae sheet for Exam #2 can be found here
04/14 TSK: Ch.13: 13.1-13.5 TSK: Ch.13: Q:13.1-13.6; Pr:13.1,13.5,13.14-16. Solutions to Homework Problem Set #5 can be found here
04/09 Ch.18: 18.3-18.6, (18.7-18.8) Ch.18: Q:18.3,18.4,18.7; Pr: 18.2,18.3. (1)Show that alpha and beta are the eigenfunctions of the I^2 operator. (2) Show that (alpha +beta)/sqrt(2) and (alpha-beta)/sqrt(2) are eigenfunctions of the Ix operator, determine the eigenvalues.
04/07 Ch.18: 18.1,18.2,18.11 Ch.18: Q: 18.2; Pr:18.1. Solutions to Homework Problem Set #4 can be found here
04/02 Ch.10: 10.3; Ch.12: 12.1-12.3,12.5; Ch.13: 13.3,13.4 Ch.10: Pr: 10.1-10.4; Ch.12: Q: 12.3,12.3; Calculate the angle between the vector of electron's spin and the z-axis. Homework Problem Set #5 (due April 14) can be downloaded from here
03/31 Ch.9: 9.5,9.6; Ch.10:10.1-10.3,10.5,10.6 Ch.10: Q:10.3-10.5,10.7; Ch.9: Pr:9.12,9.13; For 2s orbital, calculate and the most likely distance of the electton from the nucleus.
03/26 Ch.9: 9.1-9.4 Ch.9: Q: 9.4,9.7-9.10; Pr: 9.1-9.4, + compute the number of states of electron in hydtogen atom that orrespond to a given quantum number n. Several students asked me how to solve the "electron 1n benzene" problem from your midterm exam. I've written some guidelines that should help you do this --> see solutions to Exam #1 below.
03/24 Ch.8, read to the end Ch.8: Q.8.9; Pr: 8.5,8.15,8.19-20. Homework Problem Set #4 (due March 31) can be downloaded from here. Solutoins to Exam #1 problems can be found here.
03/10 Ch.8: 8.3-8.7 Ch.8: Q: 8.3,8.4,8.6; Pr: 8.2,8.10,8.13,8.14,8.16,8.22
03/10 Ch.8: 8.1, 8.2, 8.9 Q: 8.1, Pr:8.1, Ex.Pr: 8.1,8.2
03/05 Midterm Exam #1. Ch.7:7.3-7.5,7.8 Ch.7: Q:7.3,7.4,7.7,7.8; Pr: 7.17,7.19,7.23-25,7.30
03/03   Prepare for the midterm exam. The formulae sheet for the exam can be found here. Solutions to Homework Problem Set #3 can be found here.
02/26 Ch.7: 7.2,7.7. Ch.7: Q:7.2; Pr: 7.18, 7.22. Start preparing for the midterm exam (Thu, March 5). The exam will cover all material studies so far, including today's lecture. There will be two review sessions on Wed: during my office hours (1:30-3pm) and at 4:30pm in Rm 2118 (second floor) in Biomol Sci Bldg (#296). Bring your questions.
02/24 Ch.7: 7.1,7.6. Q: 7.1,7.5; Pr: 7.1,7.3,7.11 & Example problem 7.2. Homework Problem Set #3 (due March 3) can be downloaded from here. Answers to Homework Problem Set #2 can be found here.
02/19 Ch.6: 6.1,6.3-4,(6.5-6 optional) Ch.6: Pr: 6.2,6.4-6.7; Example Problems: 6.3,6.4.
02/17 Ch.5: 5.1,5.2,5.5-5.7 Ch.5: Q: 1-4,6; Pr: 5.1,5.7. Answers to Homework Problem Set #1 can be found here.
02/12 Ch.4:4.2,4.3,5.3 Ch.4: Pr: 4.12,4.15, Ch.5: Pr: 5.3. Homework Problem Set #2 (due Feb 19) can be downloaded from here.
02/10 Ch.4: 4.2,4.4 Ch.4: Pr: 4.5, 4.8
02/05 Ch.3: 3.5, Ch.4: 4.1 Ch.4: Q:2; Pr:4.4 + do your Homework Problem set #1.
02/03 Ch.2&3 to the end Ch.2: Pr: 2.16, 2.18, 2.22, 2.26. Homework Problem Set #1 (due Feb 12) can be downloaded from here.
01/29 Ch.2: 2.1-2.5; Ch.3: 3.1-3.3 Ch.2: Q: 2.1-2.3, 2.5, 2.7, 2.8; Pr:2.7, 2.9, 2.10, 2.14
01/27 QCS: Ch.1 Questions in the end of Ch.1.
Exam # 1: Exam # 2: Final Exam:
Statistics Statistics Statistics
Solutions Solutions Solutions
     

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